This was a 2-arm parallel design randomized controlled trial in 9 sites in the southwest of England. The aim of this randomized trial was to investigate the effect of the use of a sugar-free chewing gum vs ibuprofen on reported pain in orthodontic patients. 12 Professor, Department of Orthodontics, School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom.11 Research dental hygiene therapist, School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom.10 Consultant orthodontist, Royal Cornwall Hospital NHS Trust, Truro, United Kingdom.9 Consultant orthodontist, University Hospitals Bristol NHS Trust, Bristol, United Kingdom.8 Consultant orthodontist, Royal Devon and Exeter Hospitals NHS Trust, Exeter, United Kingdom.7 Consultant orthodontist, Cheltenham Hospitals NHS Trust, Cheltenham, United Kingdom.6 Consultant orthodontist, Yeovil District Hospital HS Trust, Yeovil, United Kingdom.5 Consultant orthodontist, Musgrove Park Hospital NHS Trust, Taunton, United Kingdom.4 Visiting professor, University of Exeter Medical School, Exeter, United Kingdom.3 Associate lecturer, Open University, Bath, United Kingdom.Electronic address: 2 Consultant orthodontist, Dorchester Hospital NHS Trust, Dorchester, United Kingdom. 1 Professor, Department of Orthodontics, School of Oral and Dental Sciences, University of Bristol, Bristol, United Kingdom.
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